Your gut is vital for tryptophan conversion

Tryptophan is an essential amino acid acquired via diet.

It's a precursor to serotonin, a neurotransmitter involved in mood regulation, sleep and appetite.

  • In the human gut, tryptophan performs several key functions

  • 90% of serotonin is produced in your gut, with tryptophan being a precursor. Conversion happens via specialised intestinal cells

  • Serotonin plays a role in regulating gut motility, or the contractions that affect how quickly or slowly food moves through your digestive system

  • Tryptophan metabolism in the gut can influence the immune system via compounds that regulate responses and inflammation there

  • Your gut microbiota can metabolise tryptophan into various compounds, some of which may have effects on gut health and overall well-being

    • e.g. certain bacteria can break down tryptophan to produce metabolites (products) that influence neurotransmitter production and/or immune function

Maintaining adequate tryptophan levels in the diet is crucial for overall health, as it not only supports protein synthesis (production), but also contributes to proper neurotransmitter function and gut health.

Good dietary sources of tryptophan include

  • Protein-rich foods like turkey, chicken, fish, eggs, nuts, seeds and tofu

  • Remember, good gut health is required to break down and absorb these and other nutrients