How are histamine reactions & MCAS triggered by mould?
The link between mould illness or Chronic Inflammatory Response Syndrome (CIRS), histamine reactions and Mast Cell Activation Syndrome (MCAS) revolves around the immune response triggered by mould exposure. This can lead to histamine release and potential activation of mast cells.
Mould Illness or CIRS
Exposure to mould and its toxins can stimulate the immune system, leading to chronic inflammation and a range of symptoms in susceptible individuals
Mould exposure can contribute to histamine release either directly or by triggering immune responses, potentially exacerbating histamine-related symptomsHistamine Reactions
Histamine reactions can occur due to mould exposure, leading to symptoms such as itching, respiratory issues, skin reactions, and gastrointestinal disturbances
Mould toxins or fungal fragments can directly trigger histamine release or exacerbate existing histamine-related responses in individuals sensitive to mouldMCAS
Mould exposure can be a trigger for MCAS, leading to systemic activation of mast cells and excessive release of inflammatory mediators, including histamine
Someone with MCAS may experience exacerbated symptoms in response to mould exposure due to the dysregulated mast cell response and heightened sensitivity to various triggers beyond typical allergens
In short, mould illness or CIRS can stimulate immune responses and potentially trigger histamine release, contributing to histamine reactions.
Mould exposure can also be a trigger for MCAS, leading to systemic mast cell activation and the release of inflammatory mediators like histamine, exacerbating the complex and systemic symptoms associated with MCAS.
Understanding and addressing mould exposure is crucial in managing both histamine-related symptoms and MCAS in susceptible people