The link between low stomach acid and oxalate problems

Stomach acid is mainly hydrochloric acid (HCl), and plays a crucial role in the digestion and absorption of nutrients, as well as the regulation of gut pH (acidity) and microbial balance.

But LOW stomach acid can contribute to oxalate-related problems. Here's how...

• It can impair the breakdown of food and the absorption of nutrients, including minerals like magnesium, calcium and zinc that are essential for the metabolism and excretion of oxalates. So reduced absorption of these minerals can compromise oxalate metabolism and increase the risk of oxalate-related issues.

• It helps maintain an acidic environment in the stomach, essential for controlling the growth of bacteria and other microorganisms. Insufficient levels may lead to bacterial overgrowths there and in the small intestine, disrupting the balance of gut microbiota, which in turn can raise oxalate metabolism and absorption.

• It's also involved in the breakdown of oxalates ingested through the diet. Adequate levels help convert insoluble oxalates into soluble forms, making them easier to excrete from the body. Low stomach acid can impair this process, causing increased absorption of dietary oxalates and elevated levels.

• It can impact the absorption of oxalates from the gut. Normally, stomach acid helps maintain the solubility of oxalates in the stomach and upper intestine, preventing excessive absorption. However, reduced levels may allow more oxalates to pass into the bloodstream, increasing the systemic burden.

Factors such as dietary oxalate intake, gut health and genetic predisposition also play significant roles in oxalate metabolism and excretion.